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Small Molecule Targeting of a MicroRNA Associated with Hepatocellular Carcinoma
Development of precision therapeutics is of immense interest, particularly as applied to the treatment of cancer. By analyzing the preferred cellular RNA targets of small molecules, we discovered that 5″-azido neomycin B binds the Drosha processing site in the microRNA (miR)-525 precursor. MiR-525 c...
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| Pubblicato in: | ACS Chem Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4856042/ https://ncbi.nlm.nih.gov/pubmed/26551630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00615 |
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