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The blockade of immune checkpoints in cancer immunotherapy

Among the most promising approaches to activating therapeutic antitumour immunity is the blockade of immune checkpoints. Immune checkpoints refer to a plethora of inhibitory pathways hardwired into the immune system that are crucial for maintaining self-tolerance and modulating the duration and ampl...

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Dades bibliogràfiques
Publicat a:Nat Rev Cancer
Autor principal: Pardoll, Drew M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856023/
https://ncbi.nlm.nih.gov/pubmed/22437870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3239
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