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The blockade of immune checkpoints in cancer immunotherapy
Among the most promising approaches to activating therapeutic antitumour immunity is the blockade of immune checkpoints. Immune checkpoints refer to a plethora of inhibitory pathways hardwired into the immune system that are crucial for maintaining self-tolerance and modulating the duration and ampl...
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Publicado no: | Nat Rev Cancer |
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Autor principal: | |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4856023/ https://ncbi.nlm.nih.gov/pubmed/22437870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3239 |
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