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Mechanisms and Developmental Roles of Promoter-proximal Pausing of RNA Polymerase II

RNA polymerase II (Pol II) temporarily stops transcription after synthesizing 30–50 bases, and resumes elongation only after stimulations by various signaling molecules and developmental cues. This phenomenon, called promoter-proximal pausing, is observed in 10–50% of the entire genes from Drosophil...

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Bibliographic Details
Published in:J Stem Cell Res Ther
Main Authors: Robinson, Christine, Lowe, Matthew, Schwartz, Amanda, Kikyo, Nobuaki
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855949/
https://ncbi.nlm.nih.gov/pubmed/27158559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2157-7633.1000330
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