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Mechanisms and Developmental Roles of Promoter-proximal Pausing of RNA Polymerase II

RNA polymerase II (Pol II) temporarily stops transcription after synthesizing 30–50 bases, and resumes elongation only after stimulations by various signaling molecules and developmental cues. This phenomenon, called promoter-proximal pausing, is observed in 10–50% of the entire genes from Drosophil...

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Bibliografiske detaljer
Udgivet i:J Stem Cell Res Ther
Main Authors: Robinson, Christine, Lowe, Matthew, Schwartz, Amanda, Kikyo, Nobuaki
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855949/
https://ncbi.nlm.nih.gov/pubmed/27158559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2157-7633.1000330
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