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Mechanisms and Developmental Roles of Promoter-proximal Pausing of RNA Polymerase II

RNA polymerase II (Pol II) temporarily stops transcription after synthesizing 30–50 bases, and resumes elongation only after stimulations by various signaling molecules and developmental cues. This phenomenon, called promoter-proximal pausing, is observed in 10–50% of the entire genes from Drosophil...

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Bibliografiska uppgifter
I publikationen:J Stem Cell Res Ther
Huvudupphovsmän: Robinson, Christine, Lowe, Matthew, Schwartz, Amanda, Kikyo, Nobuaki
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855949/
https://ncbi.nlm.nih.gov/pubmed/27158559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2157-7633.1000330
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