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Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans
Recent years have witnessed a sea change in our understanding of transcription regulation: whereas traditional models focused solely on the events that brought RNA polymerase II (Pol II) to a gene promoter to initiate RNA synthesis, emerging evidence points to the pausing of Pol II during early elon...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552498/ https://ncbi.nlm.nih.gov/pubmed/22986266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3293 |
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