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Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans

Recent years have witnessed a sea change in our understanding of transcription regulation: whereas traditional models focused solely on the events that brought RNA polymerase II (Pol II) to a gene promoter to initiate RNA synthesis, emerging evidence points to the pausing of Pol II during early elon...

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Autors principals: Adelman, Karen, Lis, John T.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552498/
https://ncbi.nlm.nih.gov/pubmed/22986266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3293
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