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Mechanisms and Developmental Roles of Promoter-proximal Pausing of RNA Polymerase II

RNA polymerase II (Pol II) temporarily stops transcription after synthesizing 30–50 bases, and resumes elongation only after stimulations by various signaling molecules and developmental cues. This phenomenon, called promoter-proximal pausing, is observed in 10–50% of the entire genes from Drosophil...

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Pubblicato in:J Stem Cell Res Ther
Autori principali: Robinson, Christine, Lowe, Matthew, Schwartz, Amanda, Kikyo, Nobuaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855949/
https://ncbi.nlm.nih.gov/pubmed/27158559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2157-7633.1000330
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