Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways

BACKGROUND: Recent advances in single-cell techniques have provided the opportunity to finely dissect cellular heterogeneity within populations previously defined by “bulk” assays and to uncover rare cell types. In human hematopoiesis, megakaryocytes and erythroid cells differentiate from a shared p...

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Bibliographic Details
Published in:Genome Biol
Main Authors: Psaila, Bethan, Barkas, Nikolaos, Iskander, Deena, Roy, Anindita, Anderson, Stacie, Ashley, Neil, Caputo, Valentina S., Lichtenberg, Jens, Loaiza, Sandra, Bodine, David M., Karadimitris, Anastasios, Mead, Adam J., Roberts, Irene
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855892/
https://ncbi.nlm.nih.gov/pubmed/27142433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0939-7
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