Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways

BACKGROUND: Recent advances in single-cell techniques have provided the opportunity to finely dissect cellular heterogeneity within populations previously defined by “bulk” assays and to uncover rare cell types. In human hematopoiesis, megakaryocytes and erythroid cells differentiate from a shared p...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Psaila, Bethan, Barkas, Nikolaos, Iskander, Deena, Roy, Anindita, Anderson, Stacie, Ashley, Neil, Caputo, Valentina S., Lichtenberg, Jens, Loaiza, Sandra, Bodine, David M., Karadimitris, Anastasios, Mead, Adam J., Roberts, Irene
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855892/
https://ncbi.nlm.nih.gov/pubmed/27142433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0939-7
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