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Single-cell approaches reveal novel cellular pathways for megakaryocyte and erythroid differentiation

The classical model of hematopoiesis proposes a hierarchy in which a small number of multipotent hematopoietic stem cells (HSC) maintain all blood lineages by giving rise to progeny that pass through discrete progenitor stages. At each stage, lineage differentiation potential is restricted, coupled...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Psaila, Bethan, Mead, Adam J
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443046/
https://ncbi.nlm.nih.gov/pubmed/30728145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-11-835371
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