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PINK1 and Parkin cooperatively protect neurons against constitutively active TRP channel-induced retinal degeneration in Drosophila

Calcium has an important role in regulating numerous cellular activities. However, extremely high levels of intracellular calcium can lead to neurotoxicity, a process commonly associated with degenerative diseases. Despite the clear role of calcium cytotoxicity in mediating neuronal cell death in th...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Huang, Z, Ren, S, Jiang, Y, Wang, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855661/
https://ncbi.nlm.nih.gov/pubmed/27054334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.82
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