Function and regulation of TRPP2 ion channel revealed by a gain-of-function mutant

Mutations in polycystin-1 and transient receptor potential polycystin 2 (TRPP2) account for almost all clinically identified cases of autosomal dominant polycystic kidney disease (ADPKD), one of the most common human genetic diseases. TRPP2 functions as a cation channel in its homomeric complex and...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Arif Pavel, Mahmud, Lv, Caixia, Ng, Courtney, Yang, Lei, Kashyap, Parul, Lam, Clarissa, Valentino, Victoria, Fung, Helen Y., Campbell, Thomas, Møller, Simon Geir, Zenisek, David, Holtzman, Nathalia G., Yu, Yong
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855601/
https://ncbi.nlm.nih.gov/pubmed/27071085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517066113
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars