QUADrATiC: scalable gene expression connectivity mapping for repurposing FDA-approved therapeutics

BACKGROUND: Gene expression connectivity mapping has proven to be a powerful and flexible tool for research. Its application has been shown in a broad range of research topics, most commonly as a means of identifying potential small molecule compounds, which may be further investigated as candidates...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: O’Reilly, Paul G., Wen, Qing, Bankhead, Peter, Dunne, Philip D., McArt, Darragh G., McPherson, Suzanne, Hamilton, Peter W., Mills, Ken I., Zhang, Shu-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Software
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855472/
https://ncbi.nlm.nih.gov/pubmed/27143038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1062-1
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