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Can We Repurpose FDA-Approved Alefacept to Diminish the HIV Reservoir?

Current anti-retroviral treatment (ART) for HIV is effective in maintaining HIV at undetectable levels. However, cessation of ART results in immediate and brisk rebound of viremia to high levels. This rebound is driven by an HIV reservoir mainly enriched in memory CD4(+) T cells. In order to provide...

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Detalhes bibliográficos
Publicado no:Immunotherapy (Los Angel)
Main Authors: Zaidi, Asifa, Meng, Qinglai, Popkin, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841618/
https://ncbi.nlm.nih.gov/pubmed/27110598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/imt.1000104
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