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Can We Repurpose FDA-Approved Alefacept to Diminish the HIV Reservoir?

Current anti-retroviral treatment (ART) for HIV is effective in maintaining HIV at undetectable levels. However, cessation of ART results in immediate and brisk rebound of viremia to high levels. This rebound is driven by an HIV reservoir mainly enriched in memory CD4(+) T cells. In order to provide...

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Dettagli Bibliografici
Pubblicato in:Immunotherapy (Los Angel)
Autori principali: Zaidi, Asifa, Meng, Qinglai, Popkin, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841618/
https://ncbi.nlm.nih.gov/pubmed/27110598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/imt.1000104
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