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OX40, PD-1 and CTLA-4 are selectively expressed on tumor-infiltrating T cells in head and neck cancer

The tumor microenvironment of squamous cell carcinoma of the head and neck (SCCHN) has been shown to be immune suppressive. Therefore, strategies aimed at overcoming this issue could have a positive therapeutic impact. Hence, we investigated the expression of the known immune-modulatory proteins OX4...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Clin Transl Immunology
Main Authors: Montler, Ryan, Bell, R Bryan, Thalhofer, Colin, Leidner, Rom, Feng, Zipei, Fox, Bernard A, Cheng, Allen C, Bui, Tuan G, Tucker, Christopher, Hoen, Helena, Weinberg, Andrew
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855266/
https://ncbi.nlm.nih.gov/pubmed/27195113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2016.16
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