Timing of PD-1 blockade is critical to effective combination immunotherapy with anti-OX40

PURPOSE: Antibodies specific for inhibitory checkpoints PD-1 and CTLA-4 have shown impressive results against solid tumors. This has fueled interest in novel immunotherapy combinations to impact patients who remain refractory to checkpoint blockade monotherapy. However, how to optimally combine chec...

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Foilsithe in:Clin Cancer Res
Main Authors: Messenheimer, David J., Jensen, Shawn M., Afentoulis, Michael E., Wegmann, Keith W., Feng, Zipei, Friedman, David J., Gough, Michael J., Urba, Walter J., Fox, Bernard A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641261/
https://ncbi.nlm.nih.gov/pubmed/28855348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2677
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