OX40, PD-1 and CTLA-4 are selectively expressed on tumor-infiltrating T cells in head and neck cancer

The tumor microenvironment of squamous cell carcinoma of the head and neck (SCCHN) has been shown to be immune suppressive. Therefore, strategies aimed at overcoming this issue could have a positive therapeutic impact. Hence, we investigated the expression of the known immune-modulatory proteins OX4...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Montler, Ryan, Bell, R Bryan, Thalhofer, Colin, Leidner, Rom, Feng, Zipei, Fox, Bernard A, Cheng, Allen C, Bui, Tuan G, Tucker, Christopher, Hoen, Helena, Weinberg, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855266/
https://ncbi.nlm.nih.gov/pubmed/27195113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2016.16
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