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Age‐associated de‐repression of retrotransposons in the Drosophila fat body, its potential cause and consequence

Eukaryotic genomes contain transposable elements (TE) that can move into new locations upon activation. Since uncontrolled transposition of TEs, including the retrotransposons and DNA transposons, can lead to DNA breaks and genomic instability, multiple mechanisms, including heterochromatin‐mediated...

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Publicado en:Aging Cell
Autores principales: Chen, Haiyang, Zheng, Xiaobin, Xiao, Danqing, Zheng, Yixian
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854910/
https://ncbi.nlm.nih.gov/pubmed/27072046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12465
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