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Aging-related upregulation of the homeobox gene caudal represses intestinal stem cell differentiation in Drosophila

The differentiation efficiency of adult stem cells undergoes a significant decline in aged animals, which is closely related to the decline in organ function and age-associated diseases. However, the underlying mechanisms that ultimately lead to this observed decline of the differentiation efficienc...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Wu, Kun, Tang, Yiming, Zhang, Qiaoqiao, Zhuo, Zhangpeng, Sheng, Xiao, Huang, Jingping, Ye, Jie’er, Li, Xiaorong, Liu, Zhiming, Chen, Haiyang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284806/
https://ncbi.nlm.nih.gov/pubmed/34228720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009649
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