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Age‐associated de‐repression of retrotransposons in the Drosophila fat body, its potential cause and consequence

Eukaryotic genomes contain transposable elements (TE) that can move into new locations upon activation. Since uncontrolled transposition of TEs, including the retrotransposons and DNA transposons, can lead to DNA breaks and genomic instability, multiple mechanisms, including heterochromatin‐mediated...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Chen, Haiyang, Zheng, Xiaobin, Xiao, Danqing, Zheng, Yixian
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854910/
https://ncbi.nlm.nih.gov/pubmed/27072046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12465
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