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Rif1 and Exo1 regulate the genomic instability following telomere losses
Telomere attrition is linked to cancer, diabetes, cardiovascular disease and aging. This is because telomere losses trigger further genomic modifications, culminating with loss of cell function and malignant transformation. However, factors regulating the transition from cells with short telomeres,...
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| 出版年: | Aging Cell |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4854909/ https://ncbi.nlm.nih.gov/pubmed/27004475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12466 |
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