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Rif1 and Exo1 regulate the genomic instability following telomere losses

Telomere attrition is linked to cancer, diabetes, cardiovascular disease and aging. This is because telomere losses trigger further genomic modifications, culminating with loss of cell function and malignant transformation. However, factors regulating the transition from cells with short telomeres,...

詳細記述

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書誌詳細
出版年:Aging Cell
主要な著者: Xue, Yuan, Marvin, Marcus E., Ivanova, Iglika G., Lydall, David, Louis, Edward J., Maringele, Laura
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854909/
https://ncbi.nlm.nih.gov/pubmed/27004475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12466
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