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EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Δ mutants
We have examined the role of checkpoint pathways in responding to a yku70Δ defect in budding yeast. We show that CHK1, MEC1, and RAD9 checkpoint genes are required for efficient cell cycle arrest of yku70Δ mutants cultured at 37°C, whereas RAD17, RAD24, MEC3, DDC1, and DUN1 play insignificant roles....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2002
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC186411/ https://ncbi.nlm.nih.gov/pubmed/12154123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.225102 |
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