EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Δ mutants
We have examined the role of checkpoint pathways in responding to a yku70Δ defect in budding yeast. We show that CHK1, MEC1, and RAD9 checkpoint genes are required for efficient cell cycle arrest of yku70Δ mutants cultured at 37°C, whereas RAD17, RAD24, MEC3, DDC1, and DUN1 play insignificant roles....
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| Published in: | Genes Dev |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2002
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186411/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12154123/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.225102 |
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