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The Rad51 Pathway of Telomerase-Independent Maintenance of Telomeres Can Amplify TG(1-3) Sequences in yku and cdc13 Mutants of Saccharomyces cerevisiae

In the yeast Saccharomyces cerevisiae, Cdc13, Yku, and telomerase define three parallel pathways for telomere end protection that prevent chromosome instability and death by senescence. We report here that cdc13-1 yku70Δ mutants generated telomere deprotection-resistant cells that, in contrast with...

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Detalhes bibliográficos
Main Authors: Grandin, Nathalie, Charbonneau, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155211/
https://ncbi.nlm.nih.gov/pubmed/12748277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.11.3721-3734.2003
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