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Rif1 and Exo1 regulate the genomic instability following telomere losses
Telomere attrition is linked to cancer, diabetes, cardiovascular disease and aging. This is because telomere losses trigger further genomic modifications, culminating with loss of cell function and malignant transformation. However, factors regulating the transition from cells with short telomeres,...
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| Publicado no: | Aging Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4854909/ https://ncbi.nlm.nih.gov/pubmed/27004475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12466 |
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