Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer

Tumor–stroma interactions contribute to tumorigenesis. Tumor cells can educate the stroma at primary and distant sites to facilitate the recruitment of heterogeneous populations of immature myeloid cells, known as myeloid-derived suppressor cells (MDSCs). MDSCs suppress T cell responses and promote...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: D’Amico, Lucia, Mahajan, Sahil, Capietto, Aude-Hélène, Yang, Zhengfeng, Zamani, Ali, Ricci, Biancamaria, Bumpass, David B., Meyer, Melissa, Su, Xinming, Wang-Gillam, Andrea, Weilbaecher, Katherine, Stewart, Sheila A., DeNardo, David G., Faccio, Roberta
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854727/
https://ncbi.nlm.nih.gov/pubmed/27045006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150950
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