Phospholipase Cγ1 (PLCγ1) Controls Osteoclast Numbers via Colony-stimulating Factor 1 (CSF-1)-dependent Diacylglycerol/β-Catenin/CyclinD1 Pathway

Phospholipases Cγ (PLCγ) 1 and 2 are a class of highly homologous enzymes modulating a variety of cellular pathways through production of inositol 1,4,5-trisphosphate and diacylglycerol (DAG). Our previous studies demonstrated the importance of PLCγ2 in osteoclast (OC) differentiation by modulating...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yang, Zhengfeng, Kim, Seokho, Mahajan, Sahil, Zamani, Ali, Faccio, Roberta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270464/
https://ncbi.nlm.nih.gov/pubmed/27941021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.764928
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