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Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer

Tumor–stroma interactions contribute to tumorigenesis. Tumor cells can educate the stroma at primary and distant sites to facilitate the recruitment of heterogeneous populations of immature myeloid cells, known as myeloid-derived suppressor cells (MDSCs). MDSCs suppress T cell responses and promote...

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Библиографические подробности
Опубликовано в: :J Exp Med
Главные авторы: D’Amico, Lucia, Mahajan, Sahil, Capietto, Aude-Hélène, Yang, Zhengfeng, Zamani, Ali, Ricci, Biancamaria, Bumpass, David B., Meyer, Melissa, Su, Xinming, Wang-Gillam, Andrea, Weilbaecher, Katherine, Stewart, Sheila A., DeNardo, David G., Faccio, Roberta
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854727/
https://ncbi.nlm.nih.gov/pubmed/27045006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150950
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