Specificity of Vascular Endothelial Growth Factor Treatment for Radiation Necrosis

Recently, radiation induced necrosis in the brain has been treated using bevacizumab, an anti-VEGF antibody. We validated the VEGF specificity by comparing the therapeutic efficacy of anti-VEGF with non-specific isotype control antibody. Additionally, we found that VEGF over-expression and RN develo...

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Vydáno v:Radiother Oncol
Hlavní autoři: Perez-Torres, Carlos J., Yuan, Liya, Schmidt, Robert E., Rich, Keith M., Drzymala, Robert E., Hallahan, Dennis E., Ackerman, Joseph JH., Garbow, Joel R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854530/
https://ncbi.nlm.nih.gov/pubmed/26376163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.radonc.2015.09.004
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