Genetic Deficiency of Glutathione S-Transferase P Increases Myocardial Sensitivity to Ischemia-Reperfusion Injury

RATIONALE: Myocardial ischemia-reperfusion (I/R) results in the generation of oxygen-derived free radicals and the accumulation of lipid peroxidation-derived unsaturated aldehydes. However, the contribution of aldehydes to myocardial I/R injury has not been assessed. OBJECTIVE: We tested the hypothe...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Circ Res
Главные авторы: Conklin, Daniel J., Guo, Yiru, Jagatheesan, Ganapathy, Kilfoil, Peter, Haberzettl, Petra, Hill, Bradford G., Baba, Shahid P., Guo, Luping, Wetzelberger, Karin, Obal, Detlef, Rokosh, D. Gregg, Prough, Russell A., Prabhu, Sumanth D., Velayutham, Murugesan, Zweier, Jay L., Hoetker, David, Riggs, Daniel W., Srivastava, Sanjay, Bolli, Roberto, Bhatnagar, Aruni
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854443/
https://ncbi.nlm.nih.gov/pubmed/26169370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.114.305518
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы