Glutathione S-transferase P protects against cyclophosphamide-induced cardiotoxicity in mice

High-dose chemotherapy regimens using cyclophosphamide (CY) are frequently associated with cardiotoxicity that could lead to myocyte damage and congestive heart failure. However, the mechanisms regulating the cardiotoxic effects of CY remain unclear. Because CY is converted to an unsaturated aldehyd...

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: Conklin, Daniel J., Haberzettl, Petra, Jagatheesan, Ganapathy, Baba, Shahid, Merchant, Michael L., Prough, Russell A., Williams, Jessica D., Prabhu, Sumanth D., Bhatnagar, Aruni
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430434/
https://ncbi.nlm.nih.gov/pubmed/25868843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.03.029
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