p38 Mitogen-Activated Protein Kinase-Dependent Tumor Necrosis Factor-α-Converting Enzyme Is Important for Liver Injury in Hepatotoxic Interaction between Lipopolysaccharide and Ranitidine

Ranitidine (RAN) is one of the drugs associated with idiosyncratic adverse drug reactions (IADRs) in human patients. In rats, cotreatment with nontoxic doses of lipopolysaccharide (LPS) and RAN causes liver injury. This is a potential animal model for RAN-induced IADRs in humans. Previous studies sh...

全面介紹

Na minha lista:
書目詳細資料
發表在:J Pharmacol Exp Ther
Main Authors: Deng, Xiaomin, Lu, Jingtao, Lehman-McKeeman, Lois D., Malle, Ernst, Crandall, David L., Ganey, Patricia E., Roth, Robert A.
格式: Artigo
語言:Inglês
出版: 2008
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854327/
https://ncbi.nlm.nih.gov/pubmed/18390808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.137497
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍