Integrated clinical, whole-genome, and transcriptome analysis of multisampled lethal metastatic prostate cancer

We report the first combined analysis of whole-genome sequence, detailed clinical history, and transcriptome sequence of multiple prostate cancer metastases in a single patient (A21). Whole-genome and transcriptome sequence was obtained from nine anatomically separate metastases, and targeted DNA se...

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Bibliografiske detaljer
Udgivet i:Cold Spring Harb Mol Case Stud
Main Authors: Bova, G. Steven, Kallio, Heini M.L., Annala, Matti, Kivinummi, Kati, Högnäs, Gunilla, Häyrynen, Sergei, Rantapero, Tommi, Kivinen, Virpi, Isaacs, William B., Tolonen, Teemu, Nykter, Matti, Visakorpi, Tapio
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2016
Fag:
Research Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853517/
https://ncbi.nlm.nih.gov/pubmed/27148588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a000752
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