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mTORC1 directly phosphorylates and activates ERα upon estrogen stimulation
Breast cancer is the leading cause of cancer-related deaths among women. Approximately 75% of breast cancers are estrogen receptor α (ERα) positive, underscoring the dependence of cancer cells on estrogen for growth and survival. Patients treated with endocrine therapy often develop resistance, eith...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4853282/ https://ncbi.nlm.nih.gov/pubmed/26522726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.414 |
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