Overexpression of apolipoprotein E in transgenic mice: marked reduction in plasma lipoproteins except high density lipoprotein and resistance against diet-induced hypercholesterolemia.

Apolipoprotein E (apoE) has a high affinity to cell-surface low density lipoprotein (LDL) receptor. To determine the role of apoE in plasma lipoprotein metabolism, transgenic mouse lines with integrated rat apoE gene under the control of the metallothionein promoter were established. We found that a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Shimano, H, Yamada, N, Katsuki, M, Shimada, M, Gotoda, T, Harada, K, Murase, T, Fukazawa, C, Takaku, F, Yazaki, Y
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC48530/
https://ncbi.nlm.nih.gov/pubmed/1542669
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados