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EZH2 regulates neuroepithelium structure and neuroblast proliferation by repressing p21

The function of EZH2 as a transcription repressor is well characterized. However, its role during vertebrate development is still poorly understood, particularly in neurogenesis. Here, we uncover the role of EZH2 in controlling the integrity of the neural tube and allowing proper progenitor prolifer...

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Библиографические подробности
Опубликовано в: :Open Biol
Главные авторы: Akizu, Naiara, García, María Alejandra, Estarás, Conchi, Fueyo, Raquel, Badosa, Carmen, de la Cruz, Xavier, Martínez-Balbás, Marian A.
Формат: Artigo
Язык:Inglês
Опубликовано: The Royal Society 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852452/
https://ncbi.nlm.nih.gov/pubmed/27248655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150227
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