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EZH2 regulates neuroepithelium structure and neuroblast proliferation by repressing p21

The function of EZH2 as a transcription repressor is well characterized. However, its role during vertebrate development is still poorly understood, particularly in neurogenesis. Here, we uncover the role of EZH2 in controlling the integrity of the neural tube and allowing proper progenitor prolifer...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Akizu, Naiara, García, María Alejandra, Estarás, Conchi, Fueyo, Raquel, Badosa, Carmen, de la Cruz, Xavier, Martínez-Balbás, Marian A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852452/
https://ncbi.nlm.nih.gov/pubmed/27248655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150227
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