Involvement of chromatin and histone deacetylation in SV40 T antigen transcription regulation

Simian Virus 40 (SV40) large T antigen (T Ag) is a multifunctional viral oncoprotein that regulates viral and cellular transcriptional activity. However, the mechanisms by which such regulation occurs remain unclear. Here we show that T antigen represses CBP-mediated transcriptional activity. This r...

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Библиографические подробности
Главные авторы: Valls, Ester, Blanco-García, Noemí, Aquizu, Naiara, Piedra, David, Estarás, Conchi, de la Cruz, Xavier, Martínez-Balbás, Marian A.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2007
Предметы:
Molecular Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874590/
https://ncbi.nlm.nih.gov/pubmed/17341466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1113
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