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Unwinding of chromatin by the SV40 large T antigen DNA helicase.

We have analysed the unwinding of nucleosomally organized DNA by simian virus 40 large tumour (T) antigen. Isolated T antigen can bind to existing nucleosome cores containing the viral replication origin sequence, which results in displacement of the histone octamer and unwinding of the DNA. However...

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Sonraí Bibleagrafaíochta
Main Authors: Ramsperger, U, Stahl, H
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1995
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC394383/
https://ncbi.nlm.nih.gov/pubmed/7621834
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