EZH2 regulates neuroepithelium structure and neuroblast proliferation by repressing p21

The function of EZH2 as a transcription repressor is well characterized. However, its role during vertebrate development is still poorly understood, particularly in neurogenesis. Here, we uncover the role of EZH2 in controlling the integrity of the neural tube and allowing proper progenitor prolifer...

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Bibliographic Details
Published in:Open Biol
Main Authors: Akizu, Naiara, García, María Alejandra, Estarás, Conchi, Fueyo, Raquel, Badosa, Carmen, de la Cruz, Xavier, Martínez-Balbás, Marian A.
Format: Artigo
Language:Inglês
Published: The Royal Society 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852452/
https://ncbi.nlm.nih.gov/pubmed/27248655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150227
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