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Combined Treatment with Morphine and Δ(9)-Tetrahydrocannabinol in Rhesus Monkeys: Antinociceptive Tolerance and Withdrawal

Opioid receptor agonists are effective for treating pain; however, tolerance and dependence can develop with repeated use. Combining opioids with cannabinoids can enhance their analgesic potency, although it is less clear whether combined treatment alters opioid tolerance and dependence. In this stu...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Gerak, L. R., France, C. P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851324/
https://ncbi.nlm.nih.gov/pubmed/26937020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.231381
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