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Combined Treatment with Morphine and Δ(9)-Tetrahydrocannabinol in Rhesus Monkeys: Antinociceptive Tolerance and Withdrawal

Opioid receptor agonists are effective for treating pain; however, tolerance and dependence can develop with repeated use. Combining opioids with cannabinoids can enhance their analgesic potency, although it is less clear whether combined treatment alters opioid tolerance and dependence. In this stu...

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Bibliografische gegevens
Gepubliceerd in:J Pharmacol Exp Ther
Hoofdauteurs: Gerak, L. R., France, C. P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Pharmacology and Experimental Therapeutics 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851324/
https://ncbi.nlm.nih.gov/pubmed/26937020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.231381
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