Apparent Inverse Relationship between Cannabinoid Agonist Efficacy and Tolerance/Cross-Tolerance Produced by Δ(9)-Tetrahydrocannabinol Treatment in Rhesus Monkeys

Synthetic cannabinoids (CBs) [naphthalen-1-yl-(1-pentylindol-3-yl) methanone (JWH-018) and naphthalen-1-yl-(1-butylindol-3-yl) methanone (JWH-073)] are marketed, sold, and used as alternatives to cannabis. Synthetic CBs appear to have effects similar to those of Δ(9)-tetrahydrocannabinol (Δ(9)-THC),...

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Detaylı Bibliyografya
Asıl Yazarlar: Hruba, Lenka, Ginsburg, Brett C., McMahon, Lance R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2012
Konular:
Behavioral Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422532/
https://ncbi.nlm.nih.gov/pubmed/22718500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.196444
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