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Apparent Inverse Relationship between Cannabinoid Agonist Efficacy and Tolerance/Cross-Tolerance Produced by Δ(9)-Tetrahydrocannabinol Treatment in Rhesus Monkeys
Synthetic cannabinoids (CBs) [naphthalen-1-yl-(1-pentylindol-3-yl) methanone (JWH-018) and naphthalen-1-yl-(1-butylindol-3-yl) methanone (JWH-073)] are marketed, sold, and used as alternatives to cannabis. Synthetic CBs appear to have effects similar to those of Δ(9)-tetrahydrocannabinol (Δ(9)-THC),...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Pharmacology and Experimental Therapeutics
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3422532/ https://ncbi.nlm.nih.gov/pubmed/22718500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.196444 |
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