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Sequence diversity of NanA manifests in distinct enzyme kinetics and inhibitor susceptibility
Streptococcus pneumoniae is the leading pathogen causing bacterial pneumonia and meningitis. Its surface-associated virulence factor neuraminidase A (NanA) promotes the bacterial colonization by removing the terminal sialyl residues from glycoconjugates on eukaryotic cell surface. The predominant ro...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4850393/ https://ncbi.nlm.nih.gov/pubmed/27125351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25169 |
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