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Substrate-Driven Mapping of the Degradome by Comparison of Sequence Logos

Sequence logos are frequently used to illustrate substrate preferences and specificity of proteases. Here, we employed the compiled substrates of the MEROPS database to introduce a novel metric for comparison of protease substrate preferences. The constructed similarity matrix of 62 proteases can be...

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Bibliografiske detaljer
Main Authors: Fuchs, Julian E., von Grafenstein, Susanne, Huber, Roland G., Kramer, Christian, Liedl, Klaus R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828135/
https://ncbi.nlm.nih.gov/pubmed/24244149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003353
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