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Substrate-Driven Mapping of the Degradome by Comparison of Sequence Logos

Sequence logos are frequently used to illustrate substrate preferences and specificity of proteases. Here, we employed the compiled substrates of the MEROPS database to introduce a novel metric for comparison of protease substrate preferences. The constructed similarity matrix of 62 proteases can be...

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Hlavní autoři: Fuchs, Julian E., von Grafenstein, Susanne, Huber, Roland G., Kramer, Christian, Liedl, Klaus R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828135/
https://ncbi.nlm.nih.gov/pubmed/24244149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003353
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