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Substrate-Driven Mapping of the Degradome by Comparison of Sequence Logos

Sequence logos are frequently used to illustrate substrate preferences and specificity of proteases. Here, we employed the compiled substrates of the MEROPS database to introduce a novel metric for comparison of protease substrate preferences. The constructed similarity matrix of 62 proteases can be...

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Autors principals: Fuchs, Julian E., von Grafenstein, Susanne, Huber, Roland G., Kramer, Christian, Liedl, Klaus R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828135/
https://ncbi.nlm.nih.gov/pubmed/24244149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003353
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