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Substrate-Driven Mapping of the Degradome by Comparison of Sequence Logos

Sequence logos are frequently used to illustrate substrate preferences and specificity of proteases. Here, we employed the compiled substrates of the MEROPS database to introduce a novel metric for comparison of protease substrate preferences. The constructed similarity matrix of 62 proteases can be...

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Bibliografski detalji
Glavni autori: Fuchs, Julian E., von Grafenstein, Susanne, Huber, Roland G., Kramer, Christian, Liedl, Klaus R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828135/
https://ncbi.nlm.nih.gov/pubmed/24244149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003353
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