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Amino Acid Transport Associated to Cluster of Differentiation 98 Heavy Chain (CD98hc) Is at the Cross-road of Oxidative Stress and Amino Acid Availability

CD98hc functions as an amino acid (AA) transporter (together with another subunit) and integrin signaling enhancer. It is overexpressed in highly proliferative cells in both physiological and pathological conditions. CD98hc deletion induces strong impairment of cell proliferation in vivo and in vitr...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: de la Ballina, Laura R., Cano-Crespo, Sara, González-Muñoz, Elena, Bial, Susanna, Estrach, Soline, Cailleteau, Laurence, Tissot, Floriane, Daniel, Hannelore, Zorzano, Antonio, Ginsberg, Mark H., Palacín, Manuel, Féral, Chloé C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850307/
https://ncbi.nlm.nih.gov/pubmed/26945935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.704254
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