Amino Acid Transport Associated to Cluster of Differentiation 98 Heavy Chain (CD98hc) Is at the Cross-road of Oxidative Stress and Amino Acid Availability

CD98hc functions as an amino acid (AA) transporter (together with another subunit) and integrin signaling enhancer. It is overexpressed in highly proliferative cells in both physiological and pathological conditions. CD98hc deletion induces strong impairment of cell proliferation in vivo and in vitr...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: de la Ballina, Laura R., Cano-Crespo, Sara, González-Muñoz, Elena, Bial, Susanna, Estrach, Soline, Cailleteau, Laurence, Tissot, Floriane, Daniel, Hannelore, Zorzano, Antonio, Ginsberg, Mark H., Palacín, Manuel, Féral, Chloé C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850307/
https://ncbi.nlm.nih.gov/pubmed/26945935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.704254
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